INDIA at TCT 2025: TUXEDO-2 Trial Led by Dr Upendra Kaul Compares Next-Generation Drug-Eluting Stents in Diabetic Patients

INDIA at TCT 2025: TUXEDO-2 Trial Results

The TUXEDO-2 trial, led by Dr. Upendra Kaul, compared next-generation drug-eluting stents in diabetic patients.

In patients with diabetes and multivessel coronary artery disease (MVD), the ultra-thin biodegradable polymer sirolimus-eluting stent (Supraflex Cruz, SMT) demonstrated comparable procedural success and safety outcomes to the durable polymer everolimus-eluting stent (Xience, Abbott) when used alongside optimal medical therapy.

The TUXEDO-2 trial is the largest randomized trial to date comparing new-generation drug-eluting stents (DES) in an exclusively diabetic, high-risk population with extensive multivessel coronary disease.

Author's summary: TUXEDO-2 trial compares stents in diabetic patients.

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Medical Dialogues Medical Dialogues — 2025-10-30

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