Anti-VEGF innovations in retinal disease: From molecules to medicine | Ophthalmology Times - Clinical Insights for Eye Specialists

Anti-VEGF Innovations in Retinal Disease

Emerging anti-VEGF agents offer enhanced durability and anatomic outcomes in retinal disease.

A recent Ophthalmology Times Case-Based Roundtable discussion focused on the structural differences among newer second-generation anti-VEGF agents and their implications for clinical efficacy and treatment durability.

Real-World Experiences and Evidence

The discussion highlighted real-world experiences and evidence regarding extended treatment intervals and sustained disease control with these newer therapies.

Stewart, MD, summarized the key takeaways from the discussion.

He is a professor and the chairman emeritus of ophthalmology at Mayo Clinic in Jacksonville, Florida, and the Knights Templar Eye Foundation Inc. Professor in Ophthalmology Research.

Case Study

Stewart described an 83-year-old woman with diabetic macular edema (DME) who had undergone temporal grid laser photocoagulation for macular edema and received bevacizumab (Avastin; Genentech, Inc) intravitreal injections every 4 to 6 weeks.

Author's summary: Anti-VEGF agents improve retinal disease treatment.

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Ophthalmology Times Ophthalmology Times — 2025-10-30

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