Wide Gaps in DMARD Adherence Reporting Complicate Rheumatoid Arthritis Care
DMARD nonadherence rates in patients with RA range from 0% to 100%, with inconsistent measurement tools and few validated interventions.
There is considerable variability in how disease-modifying antirheumatic drug (DMARD) nonadherence is measured, reported, and understood in rheumatoid arthritis (RA), according to a comprehensive review published in the British Journal of Clinical Pharmacology.
The true prevalence of nonadherence to DMARDs in RA is unknown, and the factors that are associated with nonadherence have not been clearly defined.
This is further complicated by the lack of a gold-standard measure of nonadherence and the wide variety of nonadherence measures that have been used.
Researchers aimed to generate insights that could shape future research and support a framework to reduce DMARD nonadherence in practice.
Author summary: Variability in DMARD adherence measurement complicates RA care.
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